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06/29/2023
Methods for non-proportional hazards in clinical trials: A systematic review
For the analysis of time-to-event data, frequently used methods such as ...
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04/06/2023
Optimal allocation strategies in platform trials
Platform trials are randomized clinical trials that allow simultaneous c...
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02/24/2023
NCC: An R-package for analysis and simulation of platform trials with non-concurrent controls
Platform trials evaluate the efficacy of multiple treatments, allowing f...
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11/17/2022
On the use of non-concurrent controls in platform trials: A scoping review
Platform trials gained popularity during the last few years as they incr...
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09/19/2022
Use of Non-concurrent Common Control in Master Protocols in Oncology Trials: Report of an American Statistical Association Biopharmaceutical Section Open Forum Discussion
This article summarizes the discussions from the American Statistical As...
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09/16/2022
The use of external controls: To what extent can it currently be recommended?
With more and better clinical data being captured outside of clinical st...
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06/20/2022
Adaptive clinical trial designs with blinded selection of binary composite endpoints and sample size reassessment
For randomized clinical trials where a single, primary, binary endpoint ...
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02/08/2022
Online error control for platform trials
Platform trials evaluate multiple experimental treatments under a single...
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12/20/2021
Online control of the False Discovery Rate in group-sequential platform trials
When testing multiple hypotheses, a suitable error rate should be contro...
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12/13/2021
On model-based time trend adjustments in platform trials with non-concurrent controls
Platform trials can evaluate the efficacy of several treatments compared...
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02/14/2021
Optimal designs for the development of personalized treatment rules
In the present paper, personalized treatment means choosing the best tre...
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06/02/2020
Conformal prediction intervals for the individual treatment effect
We propose several prediction intervals procedures for the individual tr...
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11/24/2018