Early diagnosis of autism spectrum disorder using machine learning approaches
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Autistic Spectrum Disorder (ASD) is a neurological disease characterized by difficulties with social interaction, communication, and repetitive activities. The severity of these difficulties varies, and those with this diagnosis face unique challenges. While its primary origin lies in genetics, identifying and addressing it early can contribute to the enhancement of the condition. In recent years, machine learning-driven intelligent diagnosis has emerged as a supplement to conventional clinical approaches, aiming to address the potential drawbacks of time-consuming and costly traditional methods. In this work, we utilize different machine learning algorithms to find the most significant traits responsible for ASD and to automate the diagnostic process. We study six classification models to see which model works best to identify ASD and also study five popular clustering methods to get a meaningful insight of these ASD datasets. To find the best classifier for these binary datasets, we evaluate the models using accuracy, precision, recall, specificity, F1-score, AUC, kappa and log loss metrics. Our evaluation demonstrates that five out of the six selected models perform exceptionally, achieving a 100 ASD datasets when hyperparameters are meticulously tuned for each model. As almost all classification models are able to get 100 interested in observing the underlying insights of the datasets by implementing some popular clustering algorithms on these datasets. We calculate Normalized Mutual Information (NMI), Adjusted Rand Index (ARI) Silhouette Coefficient (SC) metrics to select the best clustering models. Our evaluation finds that spectral clustering outperforms all other benchmarking clustering models in terms of NMI ARI metrics and it also demonstrates comparability to the optimal SC achieved by k-means.
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