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04/19/2023
How to design a MAMS-ROCI (aka DURATIONS) randomised trial: the REFINE-Lung case study
Background. The DURATIONS design has been recently proposed as a practic...
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11/26/2022
Multiple imputation for logistic regression models: incorporating an interaction
Background: Multiple imputation is often used to reduce bias and gain ef...
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03/21/2022
Improving clinical trial interpretation with Acceptability Curve Estimation (ACE)
Effective decision making from randomised controlled clinical trials rel...
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02/25/2020
The DURATIONS randomised trial design: estimation targets, analysis methods and operating characteristics
Background. Designing trials to reduce treatment duration is important i...
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05/01/2019
Handling an uncertain control group event risk in non-inferiority trials: non-inferiority frontiers and the power-stabilising transformation
Background. Non-inferiority (NI) trials are increasingly used to evaluat...
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02/05/2018