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08/28/2023
Data fusion using weakly aligned sources
We introduce a new data fusion method that utilizes multiple data source...
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03/20/2023
Semiparametric inference for relative heterogeneous vaccine efficacy between strains in observational case-only studies
The aim of this manuscript is to explore semiparametric methods for infe...
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11/06/2022
A framework for leveraging machine learning tools to estimate personalized survival curves
The conditional survival function of a time-to-event outcome subject to ...
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01/22/2022
Estimation and Hypothesis Testing of Strain-Specific Vaccine Efficacy with Missing Strain Types, with Applications to a COVID-19 Vaccine Trial
Statistical methods are developed for analysis of clinical and virus gen...
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07/23/2021
Efficient nonparametric estimation of the covariate-adjusted threshold-response function, a support-restricted stochastic intervention
Identifying a biomarker or treatment-dose threshold that marks a specifi...
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07/12/2021
Assessment of Immune Correlates of Protection via Controlled Vaccine Efficacy and Controlled Risk
Immune correlates of protection (CoPs) are immunologic biomarkers accept...
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04/07/2020
A unified approach for inference on algorithm-agnostic variable importance
In many applications, it is of interest to assess the relative contribut...
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03/30/2020
Efficient nonparametric inference on the effects of stochastic interventions under two-phase sampling, with applications to vaccine efficacy trials
The advent and subsequent widespread availability of preventive vaccines...
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06/20/2019
Ongoing Vaccine and Monoclonal Antibody HIV Prevention Efficacy Trials and Considerations for Sequel Efficacy Trial Designs
Four randomized placebo-controlled efficacy trials of a candidate vaccin...
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11/09/2018
Post-randomization Biomarker Effect Modification in an HIV Vaccine Clinical Trial
While the HVTN 505 trial showed no overall efficacy of the tested vaccin...
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01/25/2018
Pharmacokinetics Simulations for Studying Correlates of Prevention Efficacy of Passive HIV-1 Antibody Prophylaxis in the Antibody Mediated Prevention (AMP) Study
A key objective in two phase 2b AMP clinical trials of VRC01 is to evalu...
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01/25/2018